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If the absolute lymphocyte count (ALC) is low, it is called lymphocytopenia. There are many possible reasons why ALC may be low, including:
Infections: Certain viral infections such as HIV and hepatitis, as well as bacterial and fungal infections, can cause a decrease in lymphocytes.
Medications: Certain medications such as chemotherapy drugs and immunosuppressive medications can cause a decrease in lymphocytes.
Autoimmune disorders: Some autoimmune disorders, such as lupus and rheumatoid arthritis, can cause a decrease in lymphocytes.
Bone marrow disorders: Bone marrow disorders such as aplastic anemia, myelodysplastic syndrome, and leukemia can cause a decrease in lymphocytes.
Radiation therapy: Radiation therapy can cause a decrease in lymphocytes.
Other conditions: Other conditions such as malnutrition, alcoholism, and stress can cause a decrease in lymphocytes.
Lymphocytopenia can increase the risk of infections and other health complications. However, the severity of the effects of lymphocytopenia may depend on the underlying cause and the individual's health status. Therefore, it's always best to consult with a healthcare provider for a proper diagnosis and treatment plan.
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