Variant

Any change in the DNA sequence of a cell. Variants may be caused by mistakes during cell division, or they may be caused by exposure to DNA-damaging agents in the environment. Variants can be harmful, beneficial, or have no effect. If they occur in cells that make eggs or sperm, they can be inherited; if variants occur in other types of cells, they are not inherited. Certain variants may lead to cancer or other diseases. A variant is sometimes called a mutation.

Related Medical Acronym & Abbreviation

• Resistance-Associated Variants (RAVs)

• De novo variant

• Epigenetic variant

• Germline variant

• Missense variant

• New variant

• Nonsense variant

• Pathogenic variant

• Unclassified variant

• Variant of uncertain significance

• Variant of unknown significance

• Variant angina pectoris

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