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A type of mutation (change) in the BCR-ABL fusion protein, which is an abnormal protein found in most people with chronic myelogenous leukemia and in some with acute lymphoblastic leukemia. The T315I mutation may make cancer cells resistant (unable to respond) to anticancer drugs called tyrosine kinase inhibitors. Checking for the T315I mutation in cancer cells may help plan cancer treatment.
20000+ Medical & Health Terms for Doctors, students & patients from a medical dictionary. Our experts define difficult medical & health language in easy-to-understand explanations of each and every medical term.
Medical & Health Terms online medical dictionary provides quick & easy access to hard-to-spell and often misspelled medical & health definitions through an extensive alphabetical A-Z listing.
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