Phase 1 clinical trial

The first step in testing a new treatment in humans. A phase 1 clinical trial tests the safety, side effects, best dose, and timing of a new treatment. It may also test the best way to give a new treatment (for example, by mouth, infusion into a vein, or injection) and how the treatment affects the body. The dose is usually increased a little at a time in order to find the highest dose that does not cause harmful side effects. Phase 1 clinical trials usually include only a small number of patients who have not been helped by other treatments. Sometimes they include healthy volunteers. Also called phase I clinical trial.

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