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Rabies in humans is diagnosed through a combination of clinical evaluation and laboratory tests, including examining symptoms, history of animal exposure, and testing samples such as saliva, serum, or cerebrospinal fluid for the presence of the rabies virus or antibodies.
Yes, rabies can be diagnosed postmortem through a specialized laboratory examination of brain tissue samples. This involves testing for the presence of rabies virus antigens or genetic material using techniques like immunohistochemistry or polymerase chain reaction (PCR).
Yes, there are some challenges and limitations in rabies diagnosis. These include the need for specialized laboratory facilities and trained personnel to perform diagnostic tests, as well as the time required to obtain test results. Additionally, in some cases, the window of opportunity for accurate diagnosis may be limited, particularly in late-stage infections or when only non-specific symptoms are present.
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