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The Elisa test is not commonly used to directly detect cholera. Instead, it is primarily used to detect antibodies in the blood of individuals who have been infected with cholera. Other diagnostic tests such as stool culture, rapid diagnostic tests, and PCR are more commonly used to detect the presence of the cholera bacteria directly.
Laboratory diagnosis in medical microbiology refers to the process of identifying the causative agent of an infectious disease through various laboratory tests. This involves the examination of clinical specimens for the presence of microorganisms, as well as testing for specific antigens or antibodies in the patient's blood.
Blood tests alone cannot detect cholera. However, they can be used to detect dehydration, electrolyte imbalances, and other complications that may result from cholera infection. Specific diagnostic tests for cholera include stool culture, rapid diagnostic tests, polymerase chain reaction (PCR) tests, serology tests, and microscopic examination of stool samples.
The physical examination of cholera includes assessing the patient's vital signs, particularly their heart rate and blood pressure, as well as the degree of dehydration, skin turgor, and the presence of sunken eyes and dry mucous membranes. The abdomen is also examined for tenderness and the presence of bowel sounds. In severe cases, the examination may reveal signs of shock or even organ failure.
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