
Serum Free Light Chains Test is a blood test that helps detect and monitor conditions like multiple myeloma and amyloidosis. It's useful for assessing specific health issues.
Here are the basic details of the Serum Free Light Chains Test.
| Also Known As | Free Light Chain Assay Test |
| Type | Blood Test |
| Purpose | Detect and monitor plasma cell disorders |
| Sample Type | Serum |
| Preparation | None |
| Fasting | Not required |
| Gender | Unisex |
| Age Group | All |
| Normal Value | Varies by parameter |
| Reporting Time | A few days |
| Cost | 2500-5000 INR* |
*Serum Free Light Chains Test Price range may vary as per location, lab type, and procedure of lab test.
Serum Free Light Chains Test measures proteins linked to plasma cell disorders.
The purpose of the Serum Free Light Chains Test is to:

Here is the basic preparation for the Serum Free Light Chains Test.
Here is the basic Serum Free Light Chains Test Procedure.
Here is the normal range of the Serum Free Light Chains Test.
| Serum Free Light Chains | Normal Range (mg/L) |
|---|---|
| Kappa Free Light Chain | 3.30 - 19.40 |
| Lambda Free Light Chain | 5.71 - 26.30 |
| Kappa/Lambda Ratio | 0.26 - 1.65 |
Here is the Interpretation of the Serum Free Light Chains Test.
| KAPPA (mg/L) | LAMBDA (mg/L) | KAPPA/LAMBDA RATIO | INTERPRETATION |
|---|---|---|---|
| Normal | Normal | Normal | No significant abnormalities detected. |
| Normal | Normal | Low/High | Suggestive of Monoclonal gammopathy with possible bone marrow suppression. |
| Low | Low | Normal | Suggestive of bone marrow suppression. |
| Low | Low | Low/High | Suggestive of Monoclonal gammopathy with potential bone marrow suppression. |
| High | High | Normal | Suggestive of renal issues, excessive light chain production. |
| High | High | Low/High | Suggestive of Monoclonal gammopathy with potential renal impairment. |
| Causes | Effects |
|---|---|
| Renal impairment | Kidney damage, impaired function |
| Overproduction from inflammation | May indicate underlying health issue |
| Biclonal gammopathy | Abnormal immune response |
Elevated Serum Free Light Chains can indicate kidney problems, inflammation, or abnormal immune responses.
| Possible Causes | Effects |
|---|---|
| Plasma cell disorders (e.g., myeloma) | Increased risk, bone issues, kidney damage |
| Kidney disease or dysfunction | Elevated light chains, potential organ damage |
| Connective tissue disorders | Abnormal immune response, inflammation |
| Neurological conditions | Nervous system issues, potential complications |
| Some cancers (rarely) | Potential malignancy, health complications |
Abnormal Serum Free Light Chains results may be linked to plasma cell disorders, kidney issues, and various health complications.
Here are the specimen requirements for the Serum Free Light Chains Test.
|
Specimen |
Serum |
|
|
Volume |
0.5 mL |
|
|
Container |
Red-top tube or gel-barrier tube |
|
|
Collection |
Allow clotting and prompt serum separation to prevent hemolysis; use separate frozen specimens for multiple tests. |
|
|
Storage |
Refrigerate |
|
|
Sample Stability |
Temperature |
Period |
|
Refrigerated |
21 days |
|
|
Causes for Rejection |
Microbially-contaminated specimen; specimen containing particulate matter; lipemic or hemolyzed specimen |
|
Here is the basic limitation of Serum Free Light Chains Test.
Here are some of the risk factors of the Serum Free Light Chains Test.
Here are the Doctor's recommendations or consult a specialist after the Serum Free Light Chains Test.
| Test Results | Doctor to Consult | Reason to Visit |
|---|---|---|
| Normal | Primary Care Physician | Routine check-up or advice |
| Abnormal | Specialist (e.g., Cardiologist, Endocrinologist) | Further evaluation and treatment |
Here are the estimated Serum Free Light Chains Test Prices in India with different top cities:
|
City |
Price Range (INR)* |
|
2500-5000 |
|
|
3000-5000 |
|
|
2500-5000 |
|
|
3000-5000 |
|
|
2500-5000 |
|
|
3000-5000 |
|
|
2500-5000 |
|
|
3000-5000 |
|
|
3000-5000 |
|
|
2500-5000 |
|
|
3000-5000 |
|
|
2500-5000 |
|
|
3000-5000 |
|
|
2500-5000 |
*Prices are approximate and vary depending on a specific laboratory or healthcare facility.
Summary
Overall, Serum Free Light Chains Test assesses proteins related to plasma cell disorders, providing crucial insights into conditions like multiple myeloma and amyloidosis. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.
Reference
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