RBC Antibody Screen (Red Blood Cell Antibody) To Detect RBC Antibodies

RBC Antibody Screen (Red Blood Cell Antibody) To Detect RBC Antibodies

RBC Antibody Screen is a blood test that helps doctors make sure the right blood is given during transfusions and checks for potential issues during pregnancy to keep both mom and baby healthy.

 

RBC Antibody Screen

Here are the basic details of the RBC Antibody Screen.

Also Known As Red Blood Cell Antibody
Type Blood Test
Purpose Detect antibodies against red blood cell antigens
Sample Type Whole blood
Preparation None
Fasting Not required
Gender Unisex
Age Group All
Normal Value Negative
Reporting Time Within 24 hours
Cost 500-1000 INR*

*RBC Antibody Screen Price range may vary as per location, lab type, and lab test procedure.

 

RBC Antibody Screen Means

RBC Antibody Screen is a blood test that identifies antibodies against red blood cell antigens, aiding in transfusions and pregnancy monitoring.

  • It ensures safe blood transfusions by matching compatible blood types.
  • During pregnancy, it screens for antibodies that could harm the baby.
  • It's vital to prevent hemolytic disease of the newborn (HDN).
  • This test helps safeguard the health of both mother and baby.

 

RBC Antibody Screen Purpose

The purpose of the RBC Antibody Screen is to:

  • The main purpose of an RBC Antibody Screen is to detect antibodies directed against red blood cell antigens.
  • It ensures safe blood transfusions by matching compatible blood types.
  • During pregnancy, it screens for antibodies that could harm the baby.
  • It's essential to prevent hemolytic disease of the newborn (HDN).
  • This test safeguards the health of both mother and baby.

RBC Antibody Screen- Price, Normal Range, Result, Purpose, Procedure Meaning and Interpretation - Drlogy Test

 

RBC Antibody Screen Preparation

Here is the basic preparation for the RBC Antibody Screen.

 

Before Test

  • No specific preparation is required.
  • No need for fasting.
  • Inform your healthcare provider of any medical conditions.

 

During Test

  • A blood sample is drawn from a vein in your arm.
  • The procedure is typically quick and straightforward.
  • You may feel a slight pinch or discomfort during the blood draw.

 

After Test

  • No special post-test instructions are typically needed.
  • You can resume your usual activities.

 

RBC Antibody Screen Procedure

Here is the basic RBC Antibody Screen Procedure.

  • A blood sample drawn from a vein in the arm.
  • Sample processing in the laboratory.
  • Antibody identification test may follow if a positive result.
  • Results reported to the healthcare provider.

 

RBC Antibody Screen Result

Here is the basic reading of the RBC Antibody Screen results.

  • Positive: Antibodies against red cell antigens found.
  • Negative: No RBC antibodies detected.
  • Further tests for specificity if positive.

 

RBC Antibody Screen Normal Result

Here is the normal result of the RBC Antibody Screen.

Test Normal Result
RBC Antibody Screen Negative

 

RBC Antibody Screen Interpretation

Here is the Interpretation of the RBC Antibody Screen.

Test Result Interpretation
Positive Antibodies detected
Negative No antibodies detected

RBC Antibody Screen helps identify red blood cell antibodies for safe transfusions, with positive results indicating the presence of antibodies.

 

RBC Antibody Screen Positive

Here are the potential causes of positive RBC Antibody Screen:

Possible Causes Description
Blood transfusion Development of antibodies from past transfusions
Pregnancy Exposure to fetal blood antigens during pregnancy
Autoimmune condition The body produces antibodies against its own RBCs
Medications or infections May trigger antibody production

Positive RBC Antibody Screen may result from transfusions, pregnancy, autoimmune conditions, or medications.

 

RBC Antibody Screen Negative

Here are the potential causes of negative RBC Antibody Screen:

Possible Causes Description
No previous exposure No history of blood transfusions or pregnancies
Recent or mild exposure Antibodies may not have developed yet or are at low levels
Compatibility with donor blood Blood type matches with transfused blood
Lack of autoimmune conditions No production of antibodies against one's own RBCs
No medication-induced antibodies Medications haven't triggered antibody production

A negative RBC Antibody Screen often indicates no prior exposure, mild exposure, or compatibility with donor blood.

 

Specimen Requirements For RBC Antibody Screen

Here are the specimen requirements for the RBC Antibody Screen.

Specimen

Whole blood

Volume

4 mL

Container

Lavender-top (EDTA) tube

Collection

Specimens should be tested as soon as possible or within 72 hours of collection.

Storage Instructions

Samples that cannot be tested immediately should be stored at 2°C to 8°C. Do not freeze red cells.

Causes for Rejection

Gross hemolysis; bacterial or other contamination

 

RBC Antibody Screen is Safe?

  • RBC Antibody Screen is a safe blood test with minimal risks and side effects.
  • It is commonly performed without adverse effects, ensuring safe transfusions and pregnancies.
  • The benefits of this test in preventing complications outweigh any potential discomfort.
  • Overall, RBC Antibody Screen is generally well-tolerated and safe for patients.

 

When Do You Get RBC Antibody Screen Results? 

  • Results typically become available within a short timeframe, usually within a day.
  • The specific reporting time can vary depending on the laboratory and healthcare provider.
  • Rapid access to results allows for prompt diagnosis and treatment decisions.

 

RBC Antibody Screen Limitation

Here is the basic limitation of the RBC Antibody Screen.

  • May not identify all rare antibodies.
  • Specificity may vary among different screening tests.
  • Results can be influenced by sample quality.
  • Positive screens require further antibody identification.
  • Limited ability to diagnose other underlying conditions.

 

RBC Antibody Screen Risk Factors

Here are some of the risk factors of the RBC Antibody Screen.

  • Multiple blood transfusions increase antibody production.
  • Pregnancy with blood type incompatibility.
  • Autoimmune disorders may trigger antibody formation.
  • Medications or infections can lead to antibodies.
  • Genetic predisposition to RBC antibody production.

 

Doctor Recommendations After RBC Antibody Screen Result

 Here are the Doctor's recommendations or consult a specialist after the RBC Antibody Screen.

Test Result Doctor to Visit Reason to Visit
Positive Hematologist Evaluate and manage
Negative No Immediate Visit Routine monitoring

 

RBC Antibody Screen Price

Here are the estimated RBC Antibody Screen Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

500-1000

New Delhi

2500-5000

Bangalore

500-1000

Hyderabad

2500-5000

Kolkata

500-1000

Pune

2500-5000

Lucknow

500-1000

Noida

2500-5000

Surat

2500-5000

Gurugram

500-1000

Patna

2500-5000

Chennai

500-1000

Jaipur

2500-5000

Ahmedabad

500-1000

*RBC Antibody Screen Price are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, The RBC Antibody Screen identifies antibodies against red blood cell antigens, vital for safe transfusions and during pregnancies with blood type incompatibility. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Human red cell antigens - Wikipedia [1].
  • Red blood cell antibody screening in pregnancy - PMC - NCBI [2].
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FAQ

What is an RBC Antibody Screen?

An RBC Antibody Screen, also known as a Red Blood Cell Antibody Screen, is a blood test that checks for the presence of antibodies in a person's blood that could react with red blood cells. These antibodies can cause serious complications during blood transfusions or pregnancy, so the screen helps identify any potential risks.

What does antibody screen negative mean?

An "antibody screen negative" result in blood testing indicates that no unexpected antibodies against red blood cells (RBCs) were found in the patient's blood serum. This is a normal and desirable result, as it means the patient is not sensitized to any unusual RBC antigens.

Which antibody is present in RBC?

Antibodies against RBCs are typically present in the blood serum, not on the RBCs themselves. These antibodies, known as anti-RBC antibodies or alloantibodies, can target specific antigens on the surface of RBCs, leading to various blood-related conditions, such as hemolytic disease of the newborn or transfusion reactions.

What does antibody positive mean?

An "antibody positive" result indicates the presence of specific antibodies in the blood serum. This result can have various implications, depending on the type of antibody and the context. It may suggest sensitization to a particular antigen, which could be a concern in situations like pregnancy or blood transfusions, where incompatible antibodies can lead to adverse reactions. Further testing and evaluation are needed to determine the significance of the antibody and its potential clinical impact.

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