Prostate-Specific Antigen Test To Screen for Prostate Cancer

Prostate-Specific Antigen Test To Screen for Prostate Cancer

The Prostate-Specific Antigen Test checks for a protein related to the prostate gland. It helps detect and monitor prostate problems, including cancer.

 

PSA Test

Here are the basic details of the PSA Test.

Also Known As Prostate Specific Antigen Test, PSA Test
Type Blood Test
Purpose Detect and monitor prostate health, including cancer.
Sample Type Blood
Preparation Avoid ejaculation 24 hrs before test.
Fasting No
Gender Male
Age Group Men after age 55
Normal Value 0-4.0 ng/ml
Reporting Time One week
Cost 300-800 INR*

*Price range may vary as per location, lab type, and procedure of lab test.

 

PSA Test Means

PSA Test, or Prostate Specific Antigen Test, measures a protein in blood to assess prostate health, including cancer risk.

  • It's crucial for men, especially as they age, to monitor PSA Test results for potential prostate issues.
  • PSA Test can detect conditions like prostate cancer, benign prostatic hyperplasia (BPH), or inflammation, aiding diagnosis and treatment.
  • Preparation for PSA Test involves avoiding ejaculation 24 hours before the test for accurate results.
  • PSA Test results, usually expressed in nanograms per milliliter (ng/mL), help doctors make informed decisions about prostate health.



PSA Test Purpose

The purpose of the PSA Test is to:

  • Screens for prostate issues, like cancer or inflammation.
  • Diagnoses prostate cancer and noncancerous diseases.
  • Monitors treatment effects for cancer or BPH.
  • Assesses individual prostate health and cancer risk.
  • Part of early prostate cancer screening efforts.

PSA Test Price, Normal Range, Result, Purpose, Meaning and Interpretation - Drlogy Test

 

PSA Test Preparation

Here is the basic preparation for the PSA Test.

 

Before Test

  • Abstain from ejaculation for 24 hours before the test for accurate results.
  • Inform your doctor about medications and recent urinary system procedures.
  • Follow any specific instructions provided by your healthcare provider.

 

During Test

  • A healthcare provider draws a blood sample, usually from your arm.
  • Expect a brief sting from the needle and minor bruising.
  • The process typically takes less than five minutes.

 

After Test

  • The elastic band is removed, and the site is bandaged.
  • No special restrictions are recommended; you can resume regular activities.
  • Await results from the laboratory, which may take several days.

 

PSA Test Procedure

Here is the basic PSA Test Procedure.

  • Blood drawn from arm vein.
  • Elastic band to increase blood flow.
  • Cleaned skin, needle insertion.
  • Blood collected in sample tube.
  • Quick, relatively painless process.
  • Minor bruising, brief needle sting.
  • Bandage applied after blood draw.

 

PSA Test Result

  • PSA test results are reported in nanograms per milliliter (ng/mL).
  • Interpret based on age-adjusted reference ranges (e.g., 40-50 yrs: 0-2.5 ng/mL).
  • Consult a doctor for further evaluation if levels exceed established norms or are rapidly rising.

 

PSA Test Normal Range

Here is the normal range of the PSA Test.

Age Range PSA Normal Range (ng/mL)
40-50 years 0-2.5
50-60 years 2.5-3.5
60-70 years 3.5-4.5
70-80 years 4.5-5.5

 

PSA Test Interpretation

Here is the Interpretation of the PSA Test.

PSA Test Result (ng/mL) Interpretation
0-4.0 Typically considered within the normal range.
2.6-3.5 May be within the normal range but should be monitored.
3.6-10.0 Considered elevated; further evaluation may be needed.
Above 10.0 Significantly elevated, indicating potential concerns, including prostate cancer.

PSA test results, measured in ng/mL, guide prostate health assessment with age-adjusted reference ranges.

 

PSA Test High Levels

Here are some possible causes of high PSA levels:

Possible Causes Effects
Prostate Cancer Elevated PSA levels can be indicative of prostate cancer, especially if rapidly rising.
Prostatitis Inflammation or infection of the prostate gland can raise PSA levels.
Benign Prostatic Hyperplasia (BPH) An enlarged prostate, a noncancerous condition, can elevate PSA levels.
Recent Procedures or Biopsy Manipulation of the prostate through surgery or biopsy may temporarily raise PSA levels.
Urinary Tract Infections (UTIs) Infections in the urinary system can cause a temporary PSA increase.

Elevated PSA levels may indicate prostate cancer, prostatitis, BPH, recent procedures, or urinary tract infections.

 

PSA Test Low Levels

Here are some possible causes of low PSA levels:

Possible Causes Effects
Prostate Removal After prostate surgery, PSA levels may decrease or become undetectable.
Hormone Therapy Treatment with hormones can lower PSA levels in prostate cancer patients.
Medications Certain medications, like finasteride or dutasteride, can reduce PSA levels.
Obesity High body mass index (BMI) may be associated with lower PSA levels.
Age PSA levels may naturally decrease with age.

Low PSA levels may result from prostate removal, hormone therapy, medications, obesity, or natural age-related changes.

 

Specimen Requirements For PSA Test

Here are the specimen requirements for the PSA Test.

Specimen

Serum (preferred) or plasma

Volume

1 ml

Container

Red-top tube or gel-barrier tube,  or green-top tube

Collection

If a red-top tube or plasma is used, transfer separated serum or plasma to a plastic transport tube.

Storage

Maintain specimen at room temperature.

Sample Stability

Temperature

Period

Room temperature

7 day

Refrigerated

7 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Plasma or whole blood specimen; hemolysis

 

PSA Test is Safe?

Prostate Specific Antigen Test Generally safe and well-tolerated.

  • Minor discomfort during blood draw.
  • Rare complications (infection or bleeding) but extremely rare.
  • Discuss any concerns with your healthcare provider.

 

When Do You Get PSA Test Results? 

  • Results typically take one week.
  • Rapid tests in-office provide quicker results (within 15 minutes).
  • Lab results may require a short waiting period.
  • Consult your healthcare provider for result delivery timelines.

 

PSA Test Limitation

Here is the basic limitation of PSA Test.

  • Non-specific, can't distinguish cancer from non-cancerous conditions.
  • False positives and negatives are possible.
  • May lead to unnecessary biopsies or treatments.
  • Levels can fluctuate due to various factors.
  • Interpretation varies with age and individual health factors.

 

PSA Test Risk Factors

Here are some of the risk factors of the PSA Test.

  • Aging increases risk.
  • Family history matters.
  • African American ethnicity has higher risk.
  • Prostate inflammation or infection.
  • Recent urinary procedures.

 

Doctor Recommendations After PSA Test Result

 Here are the Doctor's recommendations or consult a specialist after the PSA Test.

PSA Test Result Doctor to Visit Reason
High Urologist Further evaluation for prostate issues.
Normal Primary care Routine follow-up and discussion.
Low Primary care Discuss any underlying conditions.

Visit a urologist for high PSA levels, while primary care for normal or low levels, to discuss further evaluation or potential underlying conditions.

 

PSA Test Price

Here are the estimated PSA Test Prices in India with different top cities:

City

Price Range (INR)*

Mumbai

300-1000

New Delhi

450-750

Bangalore

300-800

Hyderabad

400-700

Kolkata

300-800

Pune

350-800

Lucknow

300-800

Noida

350-800

Surat

350-800

Gurugram

300-800

Patna

350-800

Chennai

300-800

Jaipur

350-800

Ahmedabad

300-800

*Prices are approximate and vary depending on a specific laboratory or healthcare facility.

 

Summary

Overall, The PSA test assesses prostate health by measuring PSA levels in the blood, aiding in cancer detection and monitoring. Also check Drlogy Test for detailed information about all medical tests for patients, doctors, scholers and medical students.

 

Reference

  • Prostate-specific antigen - Wikipedia [1].
  • Prostate Specific Antigen - StatPearls [2].
5214 Likes
Share

FAQ

What is normal PSA by age?

PSA (Prostate-Specific Antigen) levels vary. Generally, a PSA of 4 ng/mL or lower is considered normal, but age-specific ranges exist. For men aged 40-49, 0-2.5 ng/mL is typical.

What is the PSA test?

The PSA test measures PSA levels in the blood. It's used to screen for prostate cancer or monitor its progression. Elevated PSA levels may indicate various prostate issues, not just cancer.

What does it mean if PSA is high?

High PSA levels may indicate prostate issues, including cancer. However, other factors like age, inflammation, or an enlarged prostate can also elevate PSA. Further tests are needed for a diagnosis.

What is a good PSA percentage?

There is no percentage for PSA; it's measured in nanograms per milliliter (ng/mL). A lower PSA is generally considered better, but what's 'good' varies among individuals and should be assessed by a doctor.

DOCTOR'S MOST TRUSTED HEALTHCARE PLATFORM

10M+

Patients

30000+

Doctors

25000+

Hospitals/Labs