Antihistone Antibodies Test

Antihistone antibodies are autoantibodies that target histones, proteins associated with DNA in the cell's nucleus. These antibodies are often measured through blood tests to diagnose autoimmune conditions, especially systemic lupus erythematosus (SLE) and drug-induced lupus.

Antihistone antibodies play a crucial role in diagnosing autoimmune diseases, as their presence can indicate underlying conditions like lupus. Identifying these antibodies helps clinicians make early and accurate diagnoses, guiding treatment decisions.

The test involves a simple blood draw, typically from a vein in your arm. The collected sample is then sent to a laboratory for analysis. It's a routine and minimally invasive procedure.

While elevated antihistone antibodies are strongly associated with lupus, they can also be found in drug-induced lupus and, less commonly, in other autoimmune diseases. This is why clinical context is crucial for interpreting the results.