Anticentromere Antibody Test

The Anticentromere Antibody (ACA) test is a blood test used to detect the presence of specific antibodies in the bloodstream. These antibodies, known as anticentromere antibodies, are associated with certain autoimmune diseases, particularly systemic sclerosis (scleroderma). ACA antibodies target structures within the cell called centromeres. The test helps in the diagnosis and monitoring of autoimmune conditions affecting the skin and internal organs.

The ACA test is typically recommended for individuals with symptoms suggestive of autoimmune diseases like systemic sclerosis. It is also used for patients with a family history of such conditions or those at higher risk. Rheumatologists, dermatologists, and other healthcare providers may order the test to confirm a diagnosis or monitor disease progression.

The ACA test is a simple blood test. A healthcare professional will draw a small sample of your blood, usually from a vein in your arm. The blood is then sent to a laboratory for analysis. Results are typically available within a few days to a week, and your healthcare provider will discuss the findings with you.

A positive ACA test suggests the presence of anticentromere antibodies in your blood, which can be indicative of autoimmune diseases, primarily limited systemic sclerosis. Further clinical evaluation and additional tests may be required to confirm the diagnosis and assess the extent of organ involvement. Early intervention and management are essential for improving outcomes.