In the context of in vitro fertilization (IVF), Progesterone supplementation is commonly used to support the development and maintenance of the uterine lining. The specific target Progesterone level for IVF can vary depending on the fertility clinic and the individual's situation. Generally, Progesterone levels above 15 ng/mL are considered desirable during IVF treatment. However, the dosage and duration of Progesterone supplementation, as well as the desired Progesterone level, are determined by the treating fertility specialist based on individual factors such as the patient's age, medical history, and response to ovarian stimulation. The Progesterone level and its management during IVF are crucial for creating an optimal uterine environment to support embryo implantation and early pregnancy. Fertility clinics closely monitor Progesterone levels and adjust supplementation accordingly to ensure adequate support. Patients undergoing IVF treatment should consultwith their fertility specialist for personalized guidance and to understand the target Progesterone levels specific to their IVF protocol. The specialist will monitor the Progesterone levels throughout the treatment cycle to optimize the chances of a successful pregnancy.