An abnormal globulin refers to an atypical or irregular level of globulin in the blood. Both low and high globulin levels can be considered abnormal depending on the individual's overall health and specific reference ranges. Abnormal globulin levels can indicate underlying medical conditions, such as malnutrition, liver or kidney disease, autoimmune disorders, chronic inflammatory conditions, certain cancers, or genetic disorders. It is important to interpret the globulin levels in conjunction with other clinical findings and diagnostic tests to determine the cause and guide proper management. Consulting a healthcare professional is necessary for accurate evaluation and treatment.