High bilirubin levels, whether direct or indirect, can lead to jaundice, a condition characterized by yellowing of the skin and eyes. Other symptoms may include fatigue, dark urine, pale stools, abdominal pain, and itching. However, it's important to note that elevated bilirubin levels can be indicative of various underlying conditions, and symptoms may vary based on the specific cause. If you experience any concerning symptoms, it's crucial to consult a healthcare professional for a proper evaluation and diagnosis.