Yes, a high CRP level can indicate the presence of an infection. CRP, or C-reactive protein, is an acute-phase reactant that the liver produces in response to inflammation. Infections, particularly bacterial infections, often trigger an inflammatory response in the body, leading to elevated CRP levels. However, it's important to note that high CRP levels can also be observed in non-infectious inflammatory conditions, such as autoimmune diseases or tissue injury. Therefore, while high CRP suggests the presence of inflammation, further evaluation is needed to determine the underlying cause, which may include infection or other inflammatory processes.