Antibiotics generally do not directly affect globulin levels. However, certain antibiotics, such as tetracyclines or sulfonamides, can rarely cause a hypersensitivity reaction called drug-induced immune hemolytic anemia. This condition may result in the destruction of red blood cells and subsequent release of globulins into the bloodstream. In such cases, globulin levels may be temporarily elevated. However, it is important to note that this is a rare side effect of specific antibiotics and not a common occurrence. Consulting a healthcare professional is recommended if you experience any unusual symptoms or adverse reactions while taking antibiotics.